منابع مشابه
Defining hormesis.
Much confusion surrounds the concept of hormesis and what its biological meaning represents. This paper provides a definition of hormesis that addresses its historical foundations, quantitative features, and underlying evolutionary and toxicologically based mechanistic strategies. Hormesis should be considered an adaptive response characterized by biphasic dose responses of generally similar qu...
متن کاملRadiation Hormesis
The word “hormesis” is derived from the Greek word “hormaein” meaning: “to excite,” which is the origin of the word “hormone.” In 1902, the English physiologist, E. Starling, discovered that an acid extract from the human duodenum contained a substance designated as secretin that, when discharged into the bloodstream, stimulated the pancreas to release its secretions when food has passed throug...
متن کاملHormesis and toxic torts.
Policy implementation of hormesis has to date focused on regulatory applications. Toxic-tort litigation may provide an alternative policy venue for real-world applications of hormesis. Businesses and government entities, who are sued by individuals claiming to have been injured by exposure to very low levels of toxic substances may defend those cases by deploying hormesis to argue that such exp...
متن کاملHormesis and medicine.
Evidence is presented which supports the conclusion that the hormetic dose-response model is the most common and fundamental in the biological and biomedical sciences, being highly generalizable across biological model, endpoint measured and chemical class and physical agent. The paper provides a broad spectrum of applications of the hormesis concept for clinical medicine including anxiety, sei...
متن کاملHormesis: Calabrese Responds
In his commentary in Environmental Health Perspectives, Calabrese (2009) offered a num ber of responses to my critique of hormesis methodology (Mushak 2009). Here I will provide a counterpoint to that effort. • Calabrese (2009) falsely asserted that I erred in calculations associated with entry and evaluatory criteria for hormesis frequency, specifically by choosing the wrong denomi nator for...
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ژورنال
عنوان ژورنال: Human & Experimental Toxicology
سال: 2015
ISSN: 0960-3271,1477-0903
DOI: 10.1177/0960327114564796